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After multiple doses, mean IGF-1 levels remained above baseline for up to 28 days, with no serious adverse reactions reported establishing the GHRH-analogue backbone as capable of sustained, clinically meaningful GH and IGF-1 axis elevation

or symptoms of significant dehydration such as dizziness, reduced urination, or inability to keep fluids down

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Its phase 2 data demonstrated substantial weight loss, and topline phase 3 results suggest the possibility of weight reduction approaching or exceeding that of earlier incretin-based pharmacotherapies

M., Pickin, K

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