Cu and Zn are at the bottom of the hydrophobic pocket
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(Cont'd) Species Test Dose Mutagenic potential Reference Chinese micronucleus 4-2500 mg/kg orally, twice with negative Siou (1981a) hamster (polychromatic erythrocytes) 24 h interval Chinese chromosome aberration 8-5000 mg/kg for 2 days inconclusive Siou (1981b) hamster (bone marrow 6 h after last dose) (bone marrow at 6, 24 and 48 h) 500, 2500, 5000 mg/kg oral equivocal Mizens et al
Eli Lilly must respond to the Center for Drug Evaluation and Research, Office of Prescription Drug Promotion within 15 working days of the receipt of the warning letter
L-Carnitine exists in two stereoisomers only the L-form is biologically active
Kaitlin Ahern Author Kaitlin Ahern is a New Jerseybased health journalist and content strategist with over a decade of experience in lifestyle media and content marketing
