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During myocardial ischemia, arising from pathological events such as unstable atherosclerotic plaque rupture, coronary occlusion, or congestive heart failure, the expression of several sHSPs is markedly upregulated

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Drug: Morphine- ~30% Bioavailability because 70% is metabolized via 1st pass effect if taken orally

Report of CIOMS Working Group V

Thymosin Alpha-1: Immune Restoration Thymosin Alpha-1 (Ta1) is a peptide derived from the thymus gland that plays a central role in immune regulationspecifically in the maturation and activation of T cells and the modulation of the innate immune response

Data were recorded with codes only, and unblinding to experimental groups for each sample only occurred once all data had been recorded