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On the other hand, tryptophan can be metabolized via the indoleamine 2,3-dioxygenase (IDO) [58, 176] or through the enzyme tryptophan-2,3-dioxygenase (TDO) to form N-formylkynurenine (Kyn) [216]
As folate deficiency leads to several pathological states, current opinions toward prevention through fortification are discussed
Contempre B, Dumont JE, Ngo B, Thilly CH, Diplock AT, Vanderpas J (1991) Effect of selenium supplementation in hypothyroid subjects of an iodine and selenium deficient area: the possible danger of indiscriminate supplementation of iodine-deficient subjects with selenium
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