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Initially corresponding beneficial central influence was seen when BPC 157 was given peripherally and a serotonin release in particular brain areas, mostly nigrostriatal, was changed

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It has also been found that ADNP is involved in histone methylation [346] and acetylation [347] upon interaction with proteins, such as the histone deacetylase sirtuin 1 (SIRT1), which regulates the transcriptional activity and epigenesis [293]

Journal of Endocrinology , 157(2), 205213

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Inflammatory and Protective Pathway Investigation: Exploring peptide involvement in cellular stress and protective signalling models