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doi: 10.1038/d41586-024-00080-1 68 YangWSSriRamaratnamRWelschMEShimadaKSkoutaRViswanathanVSet al

When readers encounter bold claims about longevity peptides, asking Which rung of the ladder does this sit on? is often more useful than asking whether the molecule sounds impressive

For example, the facultative anaerobe Enterococcus faecalis harbors a coenzyme A persulfide reductase (CoAPR) that mitigates the toxic effects of an accumulating coenzyme A persulfide (CoASSH) during sulfide stress by reducing the persulfide to coenzyme A and H 2 S, which is likely further metabolized 16

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CLONING OF AsGGT1 , AsGGT2 , AND AsGGT3 FROM GARLIC Molecular biological experiments were performed according to the standard protocols (Sambrook et al., 1989), unless otherwise specified