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The mean weight loss among participants in its phase 1 trial was 13 percent of their starting body weight after 12 weeks

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This could be related to a compensatory increase in mtDNA expression in GCs to compensate for the ovarys lack of mitochondrial energy metabolism in order to adapt to the hypoxia in the follicular development microenvironment

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doi: 10.3389/fendo.2011.00060 Bremer AA, Lustig RH: Effects of sugar-sweetened beverages on children