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When the effects of antineoplastic drugs are considered, it was demonstrated that the treatment with doxorubicin (DOX), an anticancer drug belonging to the anthracycline class, lowered GSH levels in cancer cells, and that exogenous GSH could increase cytosolic GSH levels, thus highly reducing collateral effects of DOX, such as cardiotoxicity and hepatotoxicity

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It is suitable for patients with a body mass index (BMI) of 30 or higher, or those with a BMI of 27 or higher who have additional health concerns related to their weight

However, one factor responsible for the limited effectiveness of B cell depletors in progressive MS may be resistance of leptomeningeal inflammation to even intrathecally administered agents for reasons that are not understood (Bhargava et al., 2019)

Significant negative symptoms were found in the active treatment group compared to controls but not in positive or general psychopathology [6]