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In the USA, it is typically administered as a once-weekly subcutaneous injection in the abdomen, thigh, or upper arm

Upadhyay PR, Swope VB, Starner RJ et al

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Pullar, JM., Carr, AC., Vissers, MCM

( a ) Serum acetoacetate (AcAc) and BHB levels across two independent cohorts comprising 289 patients with colorectal adenomas and carcinomas, including a test cohort (n = 100) and a validation cohort (n = 189)

This does not mean they cannot be combined, but it means researchers should be aware of the additive potential and monitor accordingly