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For example, oxidized cysteine (cystine) makes Salmonella enterica more sensitive to gentamicin by disrupting the intracellular redox balance, altered the GSH/GSSG ratio, raised ROS, and increased ferrous iron, which potentially fuels the Fenton reaction, all of which contribute to greater bactericidal activity

The thyroid gland is uniquely vulnerable to oxidative stress - it generates hydrogen peroxide as an unavoidable byproduct of hormone synthesis, making robust antioxidant protection not a luxury but a biological necessity