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Pros and cons of Ozempic and Semaglutide before and after

In the ATTAIN-1 phase 3 trial, orforglipron achieved 7.5%, 8.4%, and 11.2% weight loss after 72 weeks of treatment with 6 mg, 12 mg, and 36 mg, respectively, compared to 2.1% with placebo [32]

The injection, on the other hand, can cause injection site reactions ( e.g., redness, swelling, or bruising), which the pill avoids entirely

Some specialty pharmacies may have shipping records that include temperature data, which can help determine the extent of temperature exposure

For instance, laboratory tests from Novo Nordisk, the manufacturer of Wegovy and Ozempic, have shown that these semaglutide formulations can safely stay unrefrigerated for up to 28 days for Wegovy and 56 days for Ozempic without losing efficacy or risking contamination

Other options include 2.0 mL (5.0 mg/mL) for smaller injection volumes or 4.0 mL (2.5 mg/mL) for easier math and greater precision