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[DOI] [PMC free article] [PubMed] [Google Scholar] 273.Leenaars C.H.C., Kouwenaar C., Stafleu F.R., Bleich A., Ritskes-Hoitinga M., De Vries R.B.-M., Meijboom F.L.B

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When exogenous glutamine is depleted, AML cells significantly upregulate the expression of key SSP enzymes such as PHGDH, compensating for metabolic deficits by enhancing de novo serine synthesis to sustain cell survival and proliferation ( Research has identified that N-acetyltransferase 10 (NAT10)-mediated RNA acetylation (ac4C) promotes the uptake of exogenous serine by AML cells through enhancing the translation of the serine transporter SLC1A4

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Improved Sleep and Recovery: Deeper, more restorative sleep improves metabolism, reduces cravings, and supports hormonal healing