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Possible involvement of agmatine in neuropharmacological actions of metformin in diabetic mice

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Ling LE, Hillson JL, Tiessen RG, Bosje T, van Iersel MP, Nix DJ, et al

Symptoms of low blood sugar include shakiness, sweating, confusion, and feeling weak, which require quick treatment with fast acting carbohydrates

& MacNeil, S

In the early weeks of treatment, more frequent clinical review (for example, at four to twelve weeks) may be appropriate to assess tolerability, monitor for adverse effects, and optimise any concurrent diabetes medications