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Sample preparation : Tissue: Accordance ratio Tissue weight (g): Extract solution (mL)=1:5~10 (Suggested 0.05g of tissue with 1mL of Extract solution), homogenate on ice bath

Recognition of flavonoids results in the production of a lipo-chito-oligosaccharide termed Nod factor (NF) which can be perceived by the host legume (Barnett and Fisher, 2006)

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- Inactivation of the BAP1 gene, followed by additional mutations

It is likely that this is a consequence of increased ROS production by neutrophils in periodontitis patients

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