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Neural Regeneration Research, 17(3), 482487

Active dermatologic disease, broken or infected skin at the application site (eczema, psoriasis, infection) also a trial exclusion

Sulfur-rich foods: Garlic, onions, and cruciferous vegetables like broccoli, kale, and Brussels sprouts provide the sulfur needed for glutathione synthesis

The broader copper peptide network The paper also notes that copper peptide complexes (including the related GHK-Cu) are known to increase VEGF (vascular endothelial growth factor) production and decrease TGF-1 secretion by dermal fibroblasts

This observation hints that higher MOTS-c might correlate with better endothelial function, whereas a deficiency in MOTS-c could be linked to vascular problems

These include neuroprotective benefits, mitigating drug toxicity, anti-aging benefits, analgesic effects, and treatment of metabolic disease [21, 22, 23, 24]