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Treatment of SPF mice with vancomycin disrupts gut microbiota balance, characterized by reduced microbial diversity and altered bacterial abundance patterns

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It may only address metabolic complications like obesity in patients who meet specific FDA-approved criteria for weight management

Table 1 Changes in gut microbiota after administration of metformin therapy

This is supported by Liu et al.s work demonstrating that PA could protect the rat liver against lead-induced injury by reducing ROS production, renewing the activities of antioxidant enzymes and decreasing DNA oxidative damage (Liu et al., 2012)

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