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Future studies with larger patient cohorts should perform unbiased proteome profiling on blood and CSF samples

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This study unveils a comprehensive understanding of the intricate interaction dynamics, paving the way for subsequent investigations and clinical explorations

Resting energy expenditure, substrate oxidation rate Resting energy expenditure (REE) was calculated using Weirs equation 53 and glucose and fat oxidation according to the equation by Frayn 54 as listed below VCO 2 and VO 2 are gaseous exchanges (L/min) obtained from the calorimeter, and N is the urinary nitrogen excretion (g/min)

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