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655 In addition to its role in glycolysis and ATP production, PKM2 also regulates the redirection of glycolytic intermediates to the pentose phosphate pathway, thereby generating NADPH, which is critical for cellular redox homeostasis, 656 thus shielding cancer cells from oxidative stress

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As an antioxidant, it helps protect the skin from free radical damage/oxidative stress, thus preventing premature aging and inflammation

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