We didnt project well how many prescribers would put their patients on GLP-1s for weight loss, and the uptick was much bigger than we thought
(2022) Effect of tirzepatide versus insulin degludec on liver fat content and abdominal adipose tissue in people with type 2 diabetes (SURPASS-3 MRI): a substudy of the randomised, open-label, parallel-group, phase 3 SURPASS-3 trial Chao Liao, et al
Why Medical Supervision Matters for GLP-1 Therapy GLP-1 medications are powerful tools, but optimal results depend on proper dosing, monitoring, and ongoing adjustments
Backed by extensive scientific evidence from rigorous clinical trials and corroborated by real-world data showing substantial, sustained fat mass reduction, metabolic improvements, and enhanced quality of life, it serves as a powerful, medically supervised tool
Mix in a bit of salt and lime juice
Per current FDA guidelines, metformin is contraindicated at an estimated glomerular filtration rate (eGFR) less than 30 ml/min/1.73 kg/m 2 , and initiation is not recommended at an eGFR between 30 and 45 ml/min/1.73 kg/m 2 (17)
