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Circulating IGF1 level plays a significant role as a risk factor for the onset and development of various tumors by the increase of neoplastic cell proliferation, such as lung, breast, ovarian and colorectal cancers (Myal et al., 1984

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Regarding iNOS, it is an inducible enzyme that is produced by various cells in response to cytokines (IL-1, TNF-) 68

[DOI] [PubMed] [Google Scholar] 57.Erickson CA, Stigler KA, Corkins MR, Posey DJ, Fitzgerald JF, McDougle CJ