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Too much PEEP overstretches open units (overdistension)

**BPC-157, a synthetic gastric pentadecapeptide studied primarily in animal models for tissue repair, gut healing, and anti-inflammatory effects, remains unapproved by the FDA as a finished drug with only limited small-scale human data available.** It was placed in Category 2 in 2023 due to concerns over immunogenicity, peptide impurities, and insufficient safety information for compounding under Section 503A

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The enrichment of genes associated with regional emphysema severity with COPD-related phenotypes in these other datasets suggests that the biological processes associated with increasing emphysema severity within a patient with severe COPD also vary in individuals with earlier stages of disease

Then there's the localized camp

And I wanted to start out by saying you and I have a couple of things in common