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These characteristics are amplified among those using it for diabetes management, while those using it for the purpose of weight loss specifically are younger with higher incomes

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Berberine may affect gut bacteria and digestion to increase peptides associated with appetite (including GLP-1), and regulate genes and blood sugar production from the liver

Shes on hormone therapy to support perimenopause

The third driver, estrogen dependence, is also potentially influenced by GLP-1 medications, through a different mechanism entirely