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Salguero MV, et al

Not in human subjects

These actions improve glycemic control and promote weight loss but do not directly affect kidney function in the way that causes increased urination

We also found that among health plans that issue coverage policies, weight thresholds, diet/exercise requirements and step therapy protocols were largely in line with the FDA label

[2] [3] While semaglutide offers significant therapeutic benefits for diabetes management and weight reduction, recognizing and managing its gastrointestinal side effects remains an important aspect of treatment optimization