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LTF also increases the activity of cathepsin G, a known antibacterial enzyme (66), and broadens its substrate specificity (67), suggesting that LTF acts in concert with antibacterial neutrophil-derived enzymes in the initial phase of infection

Weight outcomes included the absolute and percent changes in weight from the index date to 1 year of post-index follow-up (index date + 365 days)

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also discussed the biological plausibility of GLP-1 RAs influencing thyroid cells, citing preclinical evidence of GLP-1 receptors in thyroid tissue

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