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Similar content being viewed by others Main Obesity is a heterogeneous, chronic condition that has grown into an extremely prevalent public health problem 1 and is one of the greatest threats to human health and well-being in the 21st century

GLP-1 Peptide Therapy refers to the use of GLP-1 receptor agonists that: Enhance satiety by slowing gastric emptying Suppress postprandial glucagon secretion Promote insulin secretion in a glucose-dependent manner Reduce caloric intake and support sustained weight loss GLP-1 Peptide Therapy has proven to be effective for chronic weight management in adults with obesity or overweight with related comorbidities

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An exploratory analysis of genetic data of patients from the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) trial showed that different haplotypes encoding for GLP-1R correlated with variable response rates to antipsychotic medications 132