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Busulfan metabolism was modeled as a GSH-dependent conjugation process, with the scaling parameter S GSH quantifying the proportionality between busulfan metabolism and corresponding GSH depletion (Equation 2).Where represents the amount of busulfan in the central compartment, represents the amount of GSH in the theoretical compartment, represents the central volume of distribution, and represents the busulfan elimination constant

15 This leads to the transcription of genes involved in osteogenesis and bone formation

time line 1

Without enough glutathione, the liver can get "backed up" during this transition from Phase I to Phase II

PMID: 145 ZhangJZhangHZhouWJiangMLinX

What is the difference between Methylcobalamin and Hydroxycobalamin B12