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Activation of GLP-1R in NAc core induces suppression of food intake (Dossat et al., 2011

Increases appetite, nutrient partitioning, fullness, and sleep quality

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A clinical trial conducted in 2023 studied the efficacy of Mounjaro in weight loss over 72 weeks

2023ZD0503400 and 2023ZD0503403) and the National Key Research and Development Program of China (Grant Nos

Other risk factors include obesity, lack of physical activity, smoking , and certain medications such as non-steroidal anti-inflammatory drugs (NSAIDs) and opioids