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Conversely, under specific conditions, glutaredoxins which depend on glutathione for their activity can also reduce oxidized thioredoxins

Some cancers are immune resistant, where some cancer cells exhibit an ability to evade treatment (see Translational Immunotherapy )

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These observations suggest that loss of IGF-1R in other retinal cells exacerbates the loss of rod function compared with the loss of IGF-1R in rod cells

It does not address the Wnt pathway, CXXC5 suppression, or the DHT-PGD2 cascade