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Reduces stomach acid production, which can decrease the acidity-driven activation of sulfate-reducing bacteria

These include: Nausea Vomiting Diarrhea Constipation Bloating and abdominal discomfort Gastrointestinal Tolerability and Dose Escalation For both tirzepatide and retatrutide, gastrointestinal symptoms are most pronounced during the initial initiation phase and immediately following a dose escalation step

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Treatment discontinuation due to gastrointestinal side effects occurred in 5.6% of semaglutide users versus 2.7% of tirzepatide users

Storing RYBELSUS 1 Store tablets in the original closed RYBELSUS bottle until ready to take one Do not use a pill organizer or other container to store RYBELSUS tablets Important note: The RYBELSUS blue cap is equipped with a drying agent to help protect the tablets from moisture, which helps preserve RYBELSUS

The active ingredient in Ozempic, semaglutide, mimics a natural hormone in the body called GLP-1