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Back Lau, J, Bloch, K, Schffer, L, et al (24 Sept 2015) 'Discovery of the once-weekly glucagon-like peptide-1 (glp-1) analogue Semaglutide', Journal Medicinal Chemistry , 58/18
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A 2022 study found that individuals gained two-thirds of the weight they lost a year after stopping 2.4 mg of semaglutide, the maximum dose
As Eli Lilly scales tirzepatide manufacturing capacity, its market share trajectory is upward and it is expected to challenge Novo Nordisk's revenue leadership within the forecast period
For someone with obesity, the cardiovascular risk reduction from losing 25% of their body weight almost certainly exceeds the risk from a 5 to 10 beat per minute resting heart rate increase
