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Sleep deprivation, which several studies have found to totally mess with GLP-1 secretion
Brennan, B
After having lost a mean of 17.3% of their bodyweight on semaglutide and 2.0% on placebo at 68 weeks, they regained 11.6% and 1.9% of weight, resulting in net losses of 5.6% and 0.1% at week 120
Benefits also included reduced hypoxic burden, lower blood pressure, and improved sleep quality
In addition to a 2030% reduction in albuminuria compared to placebo, GLP-1 receptor agonists (GLP-1RAs) decelerate the decline of estimated glomerular filtration rate (eGFR) by 12 mL/min/1.73m2 per year relative to usual therapy (Granata et al
The PREFER study was an open-label, multicenter, randomized, crossover study assessing patient preference for dulaglutide and semaglutide injection devices [130]
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