Coaxing immune cells to clear problematic proteins The amyloid antibodies appear to work by bringing plaques to the attention of immune cells in the brain called microglia
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Lee A, Kondapalli C, Virga DM, Lewis TL, Koo SY, Ashok A, Mairet-Coello G, Herzig S, Foretz M, Viollet B, Shaw R, Sproul A, Polleux F (2022) A42 oligomers trigger synaptic loss through CAMKK2-AMPK-dependent effectors coordinating mitochondrial fission and mitophagy
