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The culture was usually grown in a liquid mineral salt medium (MSM) containing (L 1 ): 3.34 g K 2 HPO 4 , 0.87 g NaH 2 PO 4 , 2.0 g NH 4 Cl , 200 mg MgSO 4 .7H 2 O , 12 mg FeSO 4 .7H 2 O , 3 mg MnSO 4

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By properly balancing endothelial nitric oxide synthase (eNOS) and inducible nitric oxide synthase (iNOS) signaling, BPC-157 down-regulates destructive pro-inflammatory cytokines without neutralizing the acute, necessary oxidative signals needed to command cellular division 6