The formula contains ingredients with modest results in small studies
Kuchay, M
Breyanzi was tagged with a boxed warning for cytokine release syndrome, neurologic toxicities and secondary hematological malignancies
References Zanker J, Sim M, Anderson K, Balogun S, Brennan-Olsen SL, Dent E, Duque G, Girgis CM, Grossmann M, Hayes A, Henwood T, Hirani V, Inderjeeth C, Iuliano S, Keogh J, Lewis JR, Lynch GS, Pasco JA, Phu S, Reijnierse EM, Russell N, Vlietstra L, Visvanathan R, Walker T, Waters DL, Yu S, Maier AB, Daly RM, Scott D
c) coupling, optionally protected Aib and His amino acid, d) acylating an epsilon amino group of lysine residue in semapeptide with an acylating agent of Formula (V), which is optionally activated, Formula V SUBSTITUTE SHEETS (RULE 26) wherein, Ri is hydroxy or a reactive ester thereof, R2 is selected from H or C1-12 alkyl
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