A 2025 retrospective cohort study found that tirzepatide was associated with a 30% to 45% lower risk of ED compared to sitagliptin, injectable semaglutide, and dulaglutide
Curcumin upregulates GAS5, which can reduce miR-10b and thereby reduce BDNF mRNA levels, or it may increase serotonin (5-HT) and dopamine levels and inhibit monoamine oxidase (MAO-A and MAO-B)
Drink plenty of water throughout the day and apply a hydrating lip balm containing ingredients like hyaluronic acid or ceramides
I have also found N-Acetyl-Cysteine , a supplement that supports liver detox capabilities, to be worth considering
A meta-analysis of these studies revealed a statistically non-significant decrease in IMT with a mean change from baseline of 0.06 [0.15, 0.03] mm
has acted as consultant, advisory board member and speaker for Boehringer Ingelheim, Eli Lilly, Novo Nordisk and Sanofi, an advisory board member Lexicon, Pfizer, ShouTi Pharma Inc, AstraZeneca and Medtronic and as a speaker for AstraZeneca, Napp Pharmaceuticals, Novartis and Amgen
