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According to the safety information, seek immediate medical care if you experience: Pancreatitis symptoms: Severe abdominal pain that doesn't go away, with or without vomiting Pain that radiates to your back Gallbladder problems: Severe abdominal pain, particularly in the upper right area Yellowing of skin or eyes (jaundice) Clay-colored stools Fever with abdominal pain Severe allergic reactions: Swelling of face, lips, tongue, or throat Difficulty breathing or swallowing Rapid heartbeat Severe rash or hives Kidney problems: Significantly decreased urination Swelling in legs or ankles Unusual fatigue or confusion Thyroid symptoms: Lump or swelling in the neck Hoarseness that doesn't improve Difficulty swallowing Shortness of breath Mental health changes: New or worsening depression Unusual mood changes Thoughts of self-harm According to the safety information, GLP-1 medications carry a boxed warning about thyroid C-cell tumors

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Metabolism-Clinical and Experimental 53 , 252259, doi:10.1016/j.metabol.2003.09.015 (2004)

Others describe the medication as very effective without specifying numbers

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