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Do the dissociative side effects of ketamine mediate its antidepressant effects

The compound has been the subject of multiple peer-reviewed studies in human participants and in vitro systems, with results published in BioMed Research International , the Archives of Facial Plastic Surgery , and dermatology and cosmetic-science literature

Friston KJ (1999)

515 Preliminary data have shown that the pharmacological effects of IGF-1 affect synaptic development primarily by modulating the MAPK and mTOR pathways, as validated in PhelanMcDermid syndrome and Rett syndrome

Microglial Sirt3 is upregulated by IF after ICH We further investigated whether Sirt3 is involved in the effects of IF on microglia activation after ICH

[8] Alicic, R