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Magnetic nanoparticles promote ferroptosis by supplying ferrous ions while enabling targeted ferroptosis cancer nanomedicines and concurrent MRI diagnostics, offering image-guided ferroptosis cancer nanotherapeutics ( 4.2.2 Advancements in imaging ferroptosis in myocardial ischemia Recent technological advancements have facilitated basic and clinical studies combining magnetic particles with imaging tools such as MRI to determine ferroptosis levels in ischemic myocardium

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It encourages the differentiation of macrophages into pro-fibrotic M2 phenotypes and an increase in extracellular matrix synthesis, which exacerbates renal fibrosis

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Adequate glutathione status in the liver upregulates vitamin D regulatory genes, which activates vitamin D