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Research has observed that GLP-1 receptor agonists may: Improve blood vessel flexibility Reduce oxidative stress Lower systemic inflammation that contributes to plaque formation Support healthier lipid metabolism Some large-scale clinical trials have demonstrated reduced cardiovascular events in patients using GLP therapieseven when weight loss was not the primary variable

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Following this, the Food and Drug Administration (FDA) gave other pharmaceutical companies permission to make non-branded, compounded versions of the drugs, using the active ingredient, semaglutide