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Such therapy should be conducted under the care of a qualified healthcare provider

The FDA-approved dose of 1.75 mg was chosen partly to balance efficacy against the nausea rate seen at higher doses in early trials

The low levels of 2-HG also explained why 2-OGDD activity was preserved following ABHD11 inhibition in CD8 + T cells

the isolated E-peptide, lacking that core, appears in several studies to act through a separate, still-uncharacterized mechanism

Patients who stay away from known triggers have dramatically lower relapse rates [5]

Despite production costs being estimated at under $5 per month, the branded pricing creates a substantial financial barrier, especially for patients requiring chronic therapy