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Effects on histology were compared between baseline and end of treatment biopsies from the same animal and scored by expert pathologists using the NASH CRN scoring criteria
Understanding whether these drugs are physically crossing into the brain or having an effect by some secondary mechanism is important because drugs that cross the blood-brain barrier can be more effective but also introduce safety risks, DiMarchi says
Novo Nordisk, a competitor to Eli Lilly, has already sought FDA approval for an oral semaglutide pill, its oral GLP-1 pill, and is expected to receive a decision by the end of this year
doi:10.1136/bmj-2024-080679 Written by Dr
Clinical evidence of antidepressant effects of insulin and anti-hyperglycemic agents and implications for the pathophysiology of depression-a literature review