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Huh D, Hamilton GA, Ingber DE (2011) From 3D cell culture to organs-on-chips

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These inconsistencies pose challenges in comparing studies, establishing definitive doseresponse relationships, and extrapolating results from rigorously characterized preparations used in clinical trials to the heterogeneous products accessible to consumers (569)

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Dopamine transporter proteins are inhibited by tesofensine, so the dopamine receptors are stimulated for a longer period after activation and the brain's reward system is amplified

Harlan R, Zhang H