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Now, he says, the shots are easy

GLP-1 semaglutide medication mimics the GLP-1 hormone that is known to increase feelings of fullness and slows gastric emptying, further increasing the feeling of fullness

doi:10.3389/fneur.2022.844697 Edison P, et al

Chronic kidney disease stage 3a or above CKD stage 3a corresponds to an estimated glomerular filtration rate (eGFR) of 45 to 59 mL/min/1.73 m for at least three months

Its not as potent as GLP1s on average, but its a pill, widely used, and may be a fit if you prefer noninjection options or cant access GLP1s

Feedback suppression of meal-induced glucagon-like peptide-1 (GLP-1) secretion mediated through elevations in intact GLP-1 caused by dipeptidyl peptidase-4 inhibition: a randomized, prospective comparison of sitagliptin and vildagliptin treatment