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Understanding the Link Between Hormones and Metabolism During the menopausal transition, estrogen and progesterone levels fluctuate unpredictably before eventually tapering off

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Although some COG0523 proteins have been reported to weakly self-associate, 125,849 the functional importance of this is not known nor are there general trends in oligomerization state that are dependent on G-nucleotide status across the COG0523 subfamily

These intracellular modifications can also indirectly (epigenetically) alter cell behaviours 6,10 and, worse, cause apoptosis 11