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[162] In March 2023, a Novo Nordisk official said, based on a randomized, double-blind study (NCT03548935 [163] ) funded by the company, that people using semaglutide to lose weight regained two-thirds of their original weight loss one year (52 weeks) after discontinuing use of the drug

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Life 11 , 417 (2021)

doi: 10.1056/NEJMra1311488

Importantly, nausea can reappear with each dose increase