10.1016/j.mam.2004.06.007 37 SilvaM
To account for design effects, the statistical computing package R version 4.4.0 (2024-04-24 ucrt) and the library survey version 4.4.2 were used to calculate standard errors
The company had been using two-piece capsules as a delivery system, but consumers complained of disgusting sulfur burps after swallowing them
However, its poorly tolerated side effect profile, leading to gastrointestinal symptoms, limits its use
The combination produced greater improvements in several fertility-related measures than either ingredient on its own, suggesting the two compounds may work particularly well together.23 Doctor's Best provides 50mcg of selenium slightly below the adult RDA of 55mcg and well below the tolerable upper intake level of 400mcg.46 While it's lower than the 200mcg used in the fertility study, it still provides meaningful nutritional support without pushing intake toward levels where selenium toxicity becomes a concern
But the study is not peer-reviewed, and three doctors who spoke with Fortune raised concerns about it being unclear on its methods, inclusion and exclusion criteria, other medications or surgeries that may not be accounted for, and whether participants continued a planned diet and exercise regimen post-medication