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Kosower et al [11] had previously reported that monobromobimane (a derivative of 1,5-diazobicyclo[3,3,0] actadiendiones) and non fluorescent compound with an electrophilic site, slowly reacted with glutathione to form fluorescent glutathione conjugate and that the reaction might be catalysed by glutathione transferase

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Its crucial to emphasize that TB4-Frag remains in the experimental stage for human use

10.1111/j.1749-6632.2010.05871.x 30 DeoS.MistryK.KakadeA.NiphadkarP

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It does not replace the stimulus