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For example, RSL3, an activator of ferroptosis, does not depend on VDAC2/3 and is selective for tumor cells carrying tumorigenic RAS

PMID: 37375654

Clinical guidelines recommend rotating IM injection sites with at least 7 days between repeat injections into the same muscle group

Endocrinol

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The maintenance frequency approach represents hybrid strategy where initial intensive treatment (daily application for 3-6 months) establishes improvements, then reduces to maintenance schedule (2-3 times weekly or every other day) rather than complete discontinuation