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Intramuscular injections are often more effective than oral supplements for severe deficiencies or neurological symptoms, as they deliver B12 directly into your bloodstream and bypass absorption issues

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Convenient in-home or hotel treatments

Long-term follow-up studies are needed to assess durability of therapeutic effects and to identify any delayed adverse effects or complications that might not be apparent in shorter-term investigations

doi: 10.1007/s00109-016-1488-y

Per the discussion above, this also has implications in the treatment of vasculogenic ED [11, 23, 24]