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In patients with unexplained liver enzyme elevations during semaglutide initiation or dose increase, prompt discontinuation often leads to rapid normalization, underscoring the importance of monitoring hepatic function closely

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Side Effects and Tolerability Both tirzepatide and semaglutide commonly cause nausea, constipation, and vomiting, especially during dose escalation

The toe is mostly probably affected but other areas like knees, heels, fingers and wrists can also be affected

[DOI] [PubMed] [Google Scholar] 13.Kahrilas PJ, Wu S, Lin S, et al